Comparison of Tissue specific expression (Rna-seq)

[detq182]

Hi

I'm wondering if exist a easy method to identify Tissue specific expression using the result of RNA-seq approach, i have 4 condition and i want to compare one to another.

What program could help me in this work?

By the way i used to use "Amoscmp" for this task, i mapping Lib1 vs Consensus Transcriptome (lib1+lib2+lib3+lib4) and see how many reads lib1 has in the consensus transcriptome and see condition especific expression but the results are unclear.

note: Not reference genome exists.

Thanks
Daniel