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Thread | Thread Starter | Forum | Replies | Last Post |
Nucleotide variation from multi-sample vcf file | kumar03 | Bioinformatics | 0 | 12-24-2015 12:27 AM |
How to calculate nucleotide diversity (pi and theta) using NextGen Data? | Genomics101 | Bioinformatics | 0 | 08-20-2013 12:06 PM |
Is nucleotide diversity higher than expected by chance? | JackieBadger | Bioinformatics | 1 | 02-21-2013 03:15 AM |
Comparing and combining vcf files | gavin.oliver | Bioinformatics | 3 | 11-30-2011 03:16 AM |
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#1 |
Junior Member
Location: West Lafayette, IN Join Date: Jan 2014
Posts: 2
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I'm looking at two homeologs and trying to gain information about their potentially different evolutionary rates. There is a publicly available dataset in the form of a VCF file from whole genome sequencing of many different, diverse cultivars. Is there a way to get nucleotide diversity (and calculate for coding sequence, synonymous, nonsynonymous etc) or Ka/Ks values for the two paralogs?
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Tags |
diversity, kaks, paralogs, vcf |
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