RNA-Seq: HITS-CLIP: panoramic views of protein-RNA regulation in living cells.

Newsbot! · 09-22-2011, 03:00 AM

Syndicated from PubMed RSS Feeds

HITS-CLIP: panoramic views of protein-RNA regulation in living cells.

Wiley Interdiscip Rev RNA. 2010 Sep;1(2):266-86

Authors: Darnell RB

Abstract
The study of gene regulation in cells has recently begun to shift from a period dominated by the study of transcription factor-DNA interactions to a new focus on RNA regulation. This was sparked by the still-emerging recognition of the central role for RNA in cellular complexity emanating from the RNA World hypothesis, and has been facilitated by technologic advances, in particular high throughput RNA sequencing and crosslinking methods (RNA-Seq, CLIP, and HITS-CLIP). This study will place these advances in context, and, focusing on CLIP, will explain the method, what it can be used for, and how to approach using it. Examples of the successes, limitations, and future of the technique will be discussed. Copyright © 2010 John Wiley & Sons, Ltd. For further resources related to this article, please visit the WIREs website.

PMID: 21935890 [PubMed - in process]

More...

Ch Tahir Shabbir · 09-11-2015, 12:48 AM

HELLO ? CAN U PLZ LET ME KNOW ABOUT MY QUESTIONS WHICH IS "how exome sequencing is related to NGS"

Similar Threads
Thread	Thread Starter	Forum	Replies	Last Post
RNA-seq from single cells?	irit	Sample Prep / Library Generation	289	02-16-2021 09:35 AM
ChIP-Seq: Physics approaches to protein interactions and gene regulation.	Newsbot!	Literature Watch	0	05-17-2011 03:10 AM
RNA-Seq: RNA-sequence analysis of human B-cells.	Newsbot!	Literature Watch	0	05-04-2011 03:50 AM
RNA-Seq: RNA-Seq Analysis of Sulfur-Deprived Chlamydomonas Cells Reveals Aspects of A	Newsbot!	Literature Watch	0	07-01-2010 03:40 AM
RNA-Seq: Transcriptome and targetome analysis in MIR155 expressing cells using RNA-se	Newsbot!	Literature Watch	0	06-30-2010 03:00 AM

09-22-2011, 03:00 AM	#1
Newsbot! RSS Posting Maniac Join Date: Feb 2008 Posts: 1,443	RNA-Seq: HITS-CLIP: panoramic views of protein-RNA regulation in living cells. Syndicated from PubMed RSS Feeds HITS-CLIP: panoramic views of protein-RNA regulation in living cells. Wiley Interdiscip Rev RNA. 2010 Sep;1(2):266-86 Authors: Darnell RB Abstract The study of gene regulation in cells has recently begun to shift from a period dominated by the study of transcription factor-DNA interactions to a new focus on RNA regulation. This was sparked by the still-emerging recognition of the central role for RNA in cellular complexity emanating from the RNA World hypothesis, and has been facilitated by technologic advances, in particular high throughput RNA sequencing and crosslinking methods (RNA-Seq, CLIP, and HITS-CLIP). This study will place these advances in context, and, focusing on CLIP, will explain the method, what it can be used for, and how to approach using it. Examples of the successes, limitations, and future of the technique will be discussed. Copyright © 2010 John Wiley & Sons, Ltd. For further resources related to this article, please visit the WIREs website. PMID: 21935890 [PubMed - in process] More...

09-11-2015, 12:48 AM	#2
Ch Tahir Shabbir Junior Member Location: islamabad, pakistan Join Date: Sep 2015 Posts: 2	how exome sequencing is related to NGS HELLO ? CAN U PLZ LET ME KNOW ABOUT MY QUESTIONS WHICH IS "how exome sequencing is related to NGS"