23andme raw Illumina intensity reads

rworthi · 11-30-2011, 04:36 PM

Has anyone been able to get the raw Illumina reads from 23andme?

I have asked repeatedly about this and just get a runaround answer. Are we not entitled to the raw data to do our own analysis, instead of just getting their list of genotype calls?

As FDA looks into regulating the DTC genotyping sector, I am advocating that the vendors be required to release the raw data to the subject.

What do you think?

- Ron

severin · 11-30-2011, 07:49 PM

My understanding is they are using chip technology and therefore there are no illumina reads. I suppose you could ask for the raw chip data.

nilshomer · 11-30-2011, 09:10 PM

I would have loved to get the probe intensities (assuming you mean your SNP chip, not the recent exome data), but they denied me too. I would love to hear if others were able to get rawer data.

rworthi · 12-01-2011, 06:56 PM

yes, I mean the Illumina OmniExpress Plus latest chip raw data. Are they even offering the exome product yet?

nilshomer · 12-01-2011, 09:29 PM

Quote:

Originally Posted by rworthi

yes, I mean the Illumina OmniExpress Plus latest chip raw data. Are they even offering the exome product yet?

Yes, I sent my sample in this week for my exome. There is a 4 month waiting period before getting the data back.

View Poll Results: Should 23andme provide the raw Illumina files?
absolutely!	7	77.78%
maybe	0	0%
no	2	22.22%
I am afraid of data	0	0%
Multiple Choice Poll. Voters: 9. You may not vote on this poll

Similar Threads
Thread	Thread Starter	Forum	Replies	Last Post
illumina raw genotype data format	nans_bn	Illumina/Solexa	1	11-21-2012 05:54 PM
View all Raw reads?	proteasome	454 Pyrosequencing	6	11-03-2011 07:35 AM
Is there any public raw intensity data from RNA-Seq	endether	Bioinformatics	0	10-10-2011 09:06 AM
Illumina Raw output	sphil	Bioinformatics	8	08-03-2011 05:42 AM
What does Illumina raw data look like?	kwebb	Bioinformatics	21	12-02-2010 05:12 PM

11-30-2011, 04:36 PM	#1
rworthi Member Location: St. Louis, MO Join Date: May 2011 Posts: 14	23andme raw Illumina intensity reads Has anyone been able to get the raw Illumina reads from 23andme? I have asked repeatedly about this and just get a runaround answer. Are we not entitled to the raw data to do our own analysis, instead of just getting their list of genotype calls? As FDA looks into regulating the DTC genotyping sector, I am advocating that the vendors be required to release the raw data to the subject. What do you think? - Ron __________________ Professor of Pharmaceutical Sciences at Southern Illinois University. Subject of the Personal Genomes Project with CGI genome sequencing, funded by a university seed grant. Annotated human and mouse genomes at the Washington University (St. Louis) GSC during Bob Waterston's tenure. Worked in nematode gene discovery at Divergence, Inc. Recent NSF grant in yeast recombinant genetics. Teach pharmacogenomics, human genomics and pharmaceutical biotechnology.

11-30-2011, 07:49 PM	#2
severin Genome Informatics Facility Location: Iowa @isugif Join Date: Sep 2009 Posts: 105	V3 chip My understanding is they are using chip technology and therefore there are no illumina reads. I suppose you could ask for the raw chip data.

12-01-2011, 06:56 PM	#4
rworthi Member Location: St. Louis, MO Join Date: May 2011 Posts: 14	yes, I mean the Illumina OmniExpress Plus latest chip raw data. Are they even offering the exome product yet? __________________ Professor of Pharmaceutical Sciences at Southern Illinois University. Subject of the Personal Genomes Project with CGI genome sequencing, funded by a university seed grant. Annotated human and mouse genomes at the Washington University (St. Louis) GSC during Bob Waterston's tenure. Worked in nematode gene discovery at Divergence, Inc. Recent NSF grant in yeast recombinant genetics. Teach pharmacogenomics, human genomics and pharmaceutical biotechnology.

11-30-2011, 09:10 PM	#3
nilshomer Nils Homer Location: Boston, MA, USA Join Date: Nov 2008 Posts: 1,285	I would have loved to get the probe intensities (assuming you mean your SNP chip, not the recent exome data), but they denied me too. I would love to hear if others were able to get rawer data.