Illumina or Solid3

f85978 · 03-30-2009, 12:21 AM

Hello, my name is Dorota. I come from Poland, but currently I am working in the Deaprtment of Genetics at King Faisla Hospital and Research Center in Riyadh. I supervise Sequencing Core Facility which is equipped with two Megabeses, two ABI 3130xl and one 3730xl. We generate up to 1500 sequencing reads per day. Our main research interest is a screening of candidate genes related to many different genetic disorders. Now we are going to get one of available NGS platforms. We are taking Illumina and Solid 3into consideration. I would be very grateful for any advices, which one will be better.
Regards,
Dorota

joa_ds · 03-30-2009, 05:52 AM

if you have access to a good analysis team, take the solid. But if you have to use existing products, i'd say, go for the illumina...

The solid produces a huge amount of data which is useless if there is noone that can write scripts and analyse it, especially with the color space. The illumina on the other hand is available with a very 'easy' pipeline, it still takes a linux guy to install and validate it, but at least you can start analysing faster than a solid run.

Similar Threads
Thread	Thread Starter	Forum	Replies	Last Post
bowtie command line for Illumina Hiseq 2000 with Illumina 1.5+ quality encoding files	rworthi	Illumina/Solexa	4	09-28-2011 12:25 PM
Convertion of SOLiD3 gff to SAM/BAM for IGV browser	hingamp	SOLiD	8	03-03-2010 02:45 PM
GAIIx VS Solid3	crapsnico	General	0	05-25-2009 07:25 AM

03-30-2009, 12:21 AM	#1
f85978 Junior Member Location: currently in Riyadh (Saudi Arabia) Join Date: Mar 2009 Posts: 3	Illumina or Solid3 Hello, my name is Dorota. I come from Poland, but currently I am working in the Deaprtment of Genetics at King Faisla Hospital and Research Center in Riyadh. I supervise Sequencing Core Facility which is equipped with two Megabeses, two ABI 3130xl and one 3730xl. We generate up to 1500 sequencing reads per day. Our main research interest is a screening of candidate genes related to many different genetic disorders. Now we are going to get one of available NGS platforms. We are taking Illumina and Solid 3into consideration. I would be very grateful for any advices, which one will be better. Regards, Dorota

03-30-2009, 05:52 AM	#2
joa_ds Member Location: belgium Join Date: Dec 2008 Posts: 52	if you have access to a good analysis team, take the solid. But if you have to use existing products, i'd say, go for the illumina... The solid produces a huge amount of data which is useless if there is noone that can write scripts and analyse it, especially with the color space. The illumina on the other hand is available with a very 'easy' pipeline, it still takes a linux guy to install and validate it, but at least you can start analysing faster than a solid run.