Tweet
For some reason this information is not readily available. Just want to know who to give the nobel prize to.
-
-
As usual, there is not a simple answer.
Frequently Rollin Hotchkiss is credited, because he was the first to describe "Epi-cytosine" as a distinct, but chemically very similar base to cytosine. (see Fig. 2)
However he established no link to epigenetics and also did not investigate the exact chemical structure of "Epi-Cytosine". The identification as 5mC was achieved by Waldo Cohn in 1951 .
-
The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist on Modified Bases...Yesterday, 07:01 AM -
Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...04-04-2024, 04:25 PM
Comment