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Old 11-05-2015, 07:30 PM   #1
mrfox
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Default tools/approaches to detect mutated pathways

hi all,

I have exome sequencing data of 50 patients. And my collaborator is specifically interested in a pathway including about 30 genes. I wonder if there is recommendation about the tool to detect significantly mutated (or malfunctioned) pathway(s).

I am trying HotNet2. Any other suggestions?

Thank you!
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Old 11-05-2015, 07:49 PM   #2
Richard Finney
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Dump your gene names into this ...

https://david.ncifcrf.gov/

"DAVID now provides a comprehensive set of functional annotation tools for investigators to understand biological meaning behind large list of genes."
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