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Old 07-15-2008, 04:26 AM   #1
baohua100
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Default population genetics parameter estimation of solexa population sequencing

My project:

A 10000bp region on chromsome 1 of human, soelxa sequencing this region of 50 individuals,



How can I estimate Pi (nucleartide diversity) ?


I know there are at list 3 factors effect :

1. sequencing error
2. alignment error
3. number of sequences be sequenced per individual is random

Last edited by baohua100; 07-16-2008 at 09:53 AM.
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Old 07-16-2008, 09:53 AM   #2
baohua100
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What's your suggestion?
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