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Old 07-17-2008, 08:47 AM   #1
baohua100
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Question SNP Allele-Frequency Determination in Pooled DNA Samples using solexa

When sequencing pooled population DNA Samples, how the relative amounts of each allele in a sample change?

After mapping the short reads, we caculate the SNP frequency(minor,major), can we use this frequency to estimate the frequency in the original sample?
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Old 07-19-2008, 12:21 AM   #2
baohua100
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anybody here give me suggestions?
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