Hello!
This question might be incredibly obvious but I have been trying to understand the chemistry behind the size selection using AMPure XP Beads to no avail. I don't understand how varying salt and PEG concentration can allow for selective binding of DNA based on the size or length of the fragment.
I was hoping that someone could explain this to me or point me to a good reference that explains the underlying mechanism behind DNA carboxyl binding size selection?
Thank you!
Lex
This question might be incredibly obvious but I have been trying to understand the chemistry behind the size selection using AMPure XP Beads to no avail. I don't understand how varying salt and PEG concentration can allow for selective binding of DNA based on the size or length of the fragment.
I was hoping that someone could explain this to me or point me to a good reference that explains the underlying mechanism behind DNA carboxyl binding size selection?
Thank you!
Lex
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