Comparison between SOLiD, Illumina MiSeq and Illumina HiSeq

NGS_New_User · 12-12-2012, 12:37 PM

My lab wants to sequence dna sample. We are aiming for a 25-30x coverage, pair-end sequence. The genome size is around 500million bp.
We are currently looking for the best sequencing platform between miseq, hiseq2000 and solid to send our samples for sequencing (to a core lab somewhere).

So, my question to all of you intelligent people is:

What are the pros and cons of those three platforms?

This question might have been asked before, maybe in a different form or context. If so, please direct me to those posts so that I can find some answers.

Thank you all

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12-12-2012, 12:37 PM	#1
NGS_New_User Member Location: USA Join Date: Sep 2012 Posts: 41	Comparison between SOLiD, Illumina MiSeq and Illumina HiSeq My lab wants to sequence dna sample. We are aiming for a 25-30x coverage, pair-end sequence. The genome size is around 500million bp. We are currently looking for the best sequencing platform between miseq, hiseq2000 and solid to send our samples for sequencing (to a core lab somewhere). So, my question to all of you intelligent people is: What are the pros and cons of those three platforms? This question might have been asked before, maybe in a different form or context. If so, please direct me to those posts so that I can find some answers. Thank you all Last edited by NGS_New_User; 12-12-2012 at 01:09 PM. Reason: Original post was misleading