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Old 10-16-2012, 01:09 PM   #1
revision
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Default Sequence alignment question Help Please Urgent!

Align the glucagon sequences for human (NM_002054.4) , cow (NM_173916.3) and chicken(Y07539.1). Nucleotide sequences
Find the conserved region that includes SRRAQDFVQWLM. Immediately after this what is asparagine substituted for in the chicken?

Options

1) glutamate
2) serine
3) glycine
4) proline
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Old 10-16-2012, 01:11 PM   #2
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This sounds suspiciously like a homework question.
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Old 10-16-2012, 01:48 PM   #3
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Urgent. Ha. The things people will do NOT to learn/understand material!
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Old 10-16-2012, 01:59 PM   #4
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The answer is D.
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Old 10-17-2012, 08:07 AM   #5
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Quote:
Originally Posted by mnkyboy View Post
The answer is D.
aka aspartate. Clearly a trick question, since that's not one of the options.
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Old 10-17-2012, 10:12 AM   #6
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So the answer is proline but after aligning the sequences and finding the conserved region how did you come to the conclusion that asparate is proline.
Can you send me a link that explains this. Thank you.
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Old 10-17-2012, 10:41 AM   #7
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The single letter code for Aspartate is 'D'.
http://upload.wikimedia.org/wikipedi...mino_Acids.svg

Makes perfect sense to me.
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Old 10-17-2012, 11:20 AM   #8
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How can the answer be aspartate if its not one of the options?
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Old 10-17-2012, 11:39 AM   #9
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Quote:
Originally Posted by revision View Post
How can the answer be aspartate if its not one of the options?
(sigh) You really don't understand?

mnkyboy said the answer was D (which is also not one of your options); D is the single-letter code for aspartate. It was a joke (indicated by ).
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Old 10-17-2012, 11:42 AM   #10
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Quote:
Tortoise: 'MU? What is this 'MU'? What about the dog? What about Buddha-nature? What's the answer?

Achilles: Oh, but 'MU' is Joshu's answer. By saying 'MU', Joshu let the other monk know that only by not asking such questions can one know the answer to them.

Tortoise: Joshu "unasked" the question.

Achilles: Exactly!

Tortoise: 'MU' sounds like a handy thing to have around. I'd like unask a question or two, sometimes. I guess I'm beginning to get the hang of Zen.
The answer is 'mu' (or D - Aspartate).
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Old 10-17-2012, 11:44 AM   #11
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Aww, you guys are teasing the teenager.

This is a site for grown-ups. People are amusing themselves at your expense. So go do your own homework.
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Old 10-17-2012, 11:46 AM   #12
HESmith
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BAMseek, I'm sure you confused revision even more (but I appreciate the Hofstadter quote).
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Old 10-17-2012, 11:57 AM   #13
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Quote:
Originally Posted by HESmith View Post
BAMseek, I'm sure you confused revision even more (but I appreciate the Hofstadter quote).
Yeah, that is probably true (and I'm glad someone knows what I am talking about).

revision -

I think you may get some more (serious) responses if you are upfront that it is a homework assignment, and you try to explain how far you have gotten with the problem. Then people may be able to nudge you in the right direction. People here are always willing to help, but I think only after they've seen you tried putting in the work yourself.

Justin
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Old 10-17-2012, 01:20 PM   #14
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Wow I'm completely speechless.
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