Hello all,
When I perform a SOAP and a Bowtie on my data (single reads) and map these reads against my reference sequence (using Sequencher), I get quite different results. When using SOAP, the reads align in blocks against the reference sequence; while for Bowtie, I get a much more equal distribution of the reads (see attachments). I used different parameters for both, but I always get the same results.
Do you experience the same?
What could be the cause of this (bioinformatics or non-bioinformatics)?
Any help more than welcome,
Thanks,
Steven
When I perform a SOAP and a Bowtie on my data (single reads) and map these reads against my reference sequence (using Sequencher), I get quite different results. When using SOAP, the reads align in blocks against the reference sequence; while for Bowtie, I get a much more equal distribution of the reads (see attachments). I used different parameters for both, but I always get the same results.
Do you experience the same?
What could be the cause of this (bioinformatics or non-bioinformatics)?
Any help more than welcome,
Thanks,
Steven
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