Hello everyone,
I am Maone, just start my project in exome sequencing + filter analysis to investigate causitive gene for a rare genetic disorder. I have no background in Linux.
So now we have got our exome sequencing result back and we would like to narrow the variants down by filters like: exclude common varients in dpSNP, only express in muscle...etc. Could anyone give me some advices on what should I do, like:
1. Is there any software windows-based but not Linux or Linux is a must-have if I want to continue my project?
2. If solely for this project, what is the extent of Linux I have to learn? Could anyone recall some good books or website to start with?
3. Where can I access these database such as muscular genes, dpSNP, fibroblast genes?
Thank you.
Maone
I am Maone, just start my project in exome sequencing + filter analysis to investigate causitive gene for a rare genetic disorder. I have no background in Linux.
So now we have got our exome sequencing result back and we would like to narrow the variants down by filters like: exclude common varients in dpSNP, only express in muscle...etc. Could anyone give me some advices on what should I do, like:
1. Is there any software windows-based but not Linux or Linux is a must-have if I want to continue my project?
2. If solely for this project, what is the extent of Linux I have to learn? Could anyone recall some good books or website to start with?
3. Where can I access these database such as muscular genes, dpSNP, fibroblast genes?
Thank you.
Maone
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