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Old 10-12-2014, 08:47 AM   #1
bios90
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Default New sequencing technologies? Want to start another sequencing company?

Anyone on top of new sequencing companies that are coming up? Off the top of my head I can list
- Base4
- 10X Technologies
- Eve Biomedical
- Quantapore
- Genapsys
- Anything else?

Does anyone know what these different companies are up to and when they will release products?

Also, will be nice to hear from anyone is brave enough to explore starting a new sequencing company. I have some ideas.
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Old 10-12-2014, 11:36 AM   #2
ECO
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10x != sequencing AFAIK.
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Old 10-12-2014, 02:11 PM   #3
bios90
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10X Technologies website says they are a sequencing company, but not clear what approach the are using.
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Old 10-13-2014, 05:30 AM   #4
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There appears to be two very similarly named companies which may be the source of the confusion.

10x Technology LLC of Libertyville, IL (http://www.10xtechnology.com) -- Micro-structure design & manufacturing (not sequencing).

10x Technologies in Pleasanton, CA (http://www.10xtechnologies.com) -- A single page web site saying they are developing new sequencing technologies; no other information provided there. Here is what they say on a job posting that went up just last week (http://www.biospace.com/jobs/job-lis...ngineer-338072):
Quote:
10X Technologies is a Silicon Valley start-up developing new technologies for breakthrough next generation sequencing applications. The core technology combines advances in chemistry, biochemistry, microfluidics and bioinformatics.
Still not a lot of information.
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Old 10-13-2014, 07:38 PM   #5
luc
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Anybody taking bets that Steve Quake is involved in 10x?
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Old 10-14-2014, 07:30 AM   #6
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Quote:
Originally Posted by luc View Post
Anybody taking bets that Steve Quake is involved in 10x?
I will...but against .

It seems that Quake's group is focused on Big Data these days rather than tech dev.

FWIW.

Austin
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Old 01-12-2015, 01:58 PM   #7
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10X Genomics is out of the bag now:

http://www.forbes.com/sites/luketimm...na-sequencing/
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Old 01-31-2015, 04:13 AM   #8
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Is X10 better than Moleculo?
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Old 02-02-2015, 09:51 AM   #9
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AllSeq has a good summary of emerging sequencing technologies.

http://allseq.com/knowledgebank/emer...nologies/genia
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Old 02-02-2015, 12:27 PM   #10
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BioNano
http://www.bionanogenomics.com/products/
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Old 02-09-2015, 12:42 PM   #11
niroshan
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Q-SEQ from QuantumDX

Alongside QuantuMDx's novel sequencing by synthesis (SBS) DNA sequencing chemistry deployed on its nanowire FET biosensors, QMDx is also developing a novel DNA sequencing technology named Q-SEQ™. This device will perform single molecule, direct read (i.e. no need for reagents or expensive fluorescent detectors), long DNA sequencing reads and is presently at the prototyping stage.

http://www.quantumdx.com/



Nabsys positional sequencing

Nabsys has designed semiconductor-based nanodetectors to enable direct electrical detection of tagged DNA.

http://nabsys.com/

Last edited by niroshan; 02-09-2015 at 12:50 PM.
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Old 02-25-2015, 09:43 AM   #12
larissa
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I was not sure if to post this here or in the Solid forum, but I figured this would work too, so anyone knows what is going on (if anything) with the Solid platform? How commonly is it (still) used?
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Old 02-26-2015, 09:02 AM   #13
AllSeq
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Quote:
Originally Posted by larissa View Post
I was not sure if to post this here or in the Solid forum, but I figured this would work too, so anyone knows what is going on (if anything) with the Solid platform? How commonly is it (still) used?
This is probably best in the SOLiD platform. But to answer your question, "Not much". On our Sequencing Marketplace, we haven't had a single request for the SOLiD platform. The unsurprising #1 request was Illumina at ~83%. #2 was a tie between PacBio and Ion Torrent (~7% each).
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Old 03-02-2015, 05:47 AM   #14
larissa
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Thanks AllSeq for the info! Btw, your knowledge base is quite helpful.
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Old 07-02-2015, 07:49 AM   #15
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Looks like GenapSys is trying to get some press via the Sigma Aldrich website, but none of the links go anywhere.
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Old 07-02-2015, 07:56 AM   #16
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GenomeWeb reported yesterday that Sigma-Aldrich was going to co-market the Genius sequencer. There was no launch date mentioned.
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Old 01-14-2016, 11:49 AM   #17
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Default NanoString Developing Novel Sequencing Chemistry Based on Optical Barcoding

At the JP Morgan Healthcare Conference, NanoString Technologies CEO Brad Gray said that the firm has been developing a novel single-molecule hybridization-based sequencing chemistry that leverages the company's optical barcoding technology.

Gray declined to provide details on the chemistry, which he dubbed Hyb&Seq, but said that it would be single-molecule, based on hybridization, and would not require amplification, the use of enzymes, or even library prep.
[Link to Genomeweb article]
[Link to NanoString Presentation]
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