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Old 06-26-2012, 03:00 AM   #1
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Default PubMed: DySC: Software for Greedy Clustering of 16S rRNA Reads.

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DySC: Software for Greedy Clustering of 16S rRNA Reads.

Bioinformatics. 2012 Jun 23;

Authors: Zheng Z, Kramer S, Schmidt B

Abstract
SUMMARY: Pyrosequencing technologies are frequently used for sequencing the 16S rRNA marker gene for profiling microbial communities. Clustering of the produced reads is an important but time-consuming task. We present DySC, a new tool based on the greedy clustering approach which uses a dynamic seeding strategy. Evaluations based on the normalized mutual information criterion show that DySC produces higher quality clusters than UCLUST and CD-HIT at a comparable runtime.Availability and Implementation: DySC, implemented in C, is available at http://code.google.com/p/dysc/ under GNU GPL license. CONTACT: bertil.schmidt@uni-mainz.de SUPPLEMENTARY INFORMATION: available at Bioinformatics online.


PMID: 22730435 [PubMed - as supplied by publisher]



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