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Old 11-24-2016, 01:58 AM   #1
Junior Member
Location: The Netherlands

Join Date: Nov 2016
Posts: 9
Post Can I use tabix on vcf.gz files?

As a beginner I might have a stupid question, but I have several VCF files of different individuals that are zipped ( .vcf.gz). I want to merge these files into one VCF file containing all individuals by using vcf-merge.

However, this requires the files to be actually zipped with bgzip and indexed with tabix. Does anyone know if I can go from a .vcf.gz file to a tabix indexed and bgzip file without uncompressing it first (it takes a lot of storage, the files are really big).

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bgzip, gzip, merge, tabix, vcf

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