Dear colleagues, I have implemented two software packages. HighSSR framework can significantly simplify development of the microsatellites (SSR) markers from the next generation sequencing reads (especially from Roche 454 GS-FLX raw reads because they are longer). The other package is for Illumina RNA-Seq transcriptome analysis in case/control studies. These are freely available from here http://maximusinuse.nmsu.edu. Please let me know your opinion about these developments, we will submit corresponding method papers for review shortly.
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by seqadmin
The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...-
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04-22-2024, 07:01 AM -
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Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...-
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04-04-2024, 04:25 PM -
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