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Old 11-14-2011, 01:33 PM   #1
stephenhart
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Question Comparing mouse and human differentially expressed genes

Hello,

I have run differential expression analyses for mouse and human using RNA-seq data. I now have a list of genes (Ensembl IDs) differentially expressed in the mouse and a list of genes differentially expressed in the human. How can I now see if there is any overlap between the lists? Clearly I cannot use the Ensembl IDs, and many gene symbols differ between mouse and human. Any advice would be appreciated.

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Stephan
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Old 11-15-2011, 09:42 AM   #2
kmcarr
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Look at this link. It's a little outdated but should give a start.
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Old 11-15-2011, 09:51 AM   #3
marcowanger
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Stephen you might want to know more on the synteny blocks between mouse and human

http://www.evolutionpages.com/Mouse%...%20synteny.htm
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Old 11-16-2011, 01:14 AM   #4
MichalO
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Quote:
Originally Posted by kmcarr View Post
Look at this link. It's a little outdated but should give a start.
Yup. Translate the Ensembl IDs from human to mouse orthologs using biomart.org - then you'll have the quite complete table.
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gene annotation, orthologues, rna seq

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