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Old 09-22-2011, 02:00 AM   #1
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Default RNA-Seq: HITS-CLIP: panoramic views of protein-RNA regulation in living cells.

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HITS-CLIP: panoramic views of protein-RNA regulation in living cells.

Wiley Interdiscip Rev RNA. 2010 Sep;1(2):266-86

Authors: Darnell RB

Abstract
The study of gene regulation in cells has recently begun to shift from a period dominated by the study of transcription factor-DNA interactions to a new focus on RNA regulation. This was sparked by the still-emerging recognition of the central role for RNA in cellular complexity emanating from the RNA World hypothesis, and has been facilitated by technologic advances, in particular high throughput RNA sequencing and crosslinking methods (RNA-Seq, CLIP, and HITS-CLIP). This study will place these advances in context, and, focusing on CLIP, will explain the method, what it can be used for, and how to approach using it. Examples of the successes, limitations, and future of the technique will be discussed. Copyright 2010 John Wiley & Sons, Ltd. For further resources related to this article, please visit the WIREs website.


PMID: 21935890 [PubMed - in process]



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Old 09-10-2015, 11:48 PM   #2
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Default how exome sequencing is related to NGS

HELLO ? CAN U PLZ LET ME KNOW ABOUT MY QUESTIONS WHICH IS "how exome sequencing is related to NGS"
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