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Research Associate - Biostatistics/Bioinformatics
Department of Plant Sciences, University of Cambridge, UK
Modelling control of meiotic recombination frequency
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Meiotic recombination generates novel combinations of genetic variation via reciprocal exchange between homologous chromosomes. To better understand this process we are generating genome-wide recombination frequency maps in the model plant Arabidopsis thaliana.
The research associate will integrate recombination frequency maps with genomic, epigenomic and population genetic data. They will then develop a quantitative model for control of recombination frequency, which will be tested using experimental genetics. This research has important implications for population genetics and food security via crop breeding.
The research associate will work jointly within Dr Ian Henderson's experimental research group and the Departmental Bioinformatics Group led by Dr Krys Kelly. The bioinformatics group currently consists of five people developing statistical methodology and analysing genome-wide patterns of small RNAs and epigenetic information in association with Prof Sir David Baulcombe.
Applicants should have a Ph.D and substantial experience of a statistical language (e.g. R, Matlab). Experience in statistics, statistical genetics, quantitative genetics or genomics would also be beneficial.
Vacancy Reference No: PD09942. Salary: £27,319-£35,646 pa.
The post is available for 2 years, in the first instance.
Download the further particulars and details of how to apply from http://www.plantsci.cam.ac.uk/jobs/index.html.
Closing date is 12 noon on 16 December 2011.
Department of Plant Sciences, University of Cambridge, UK
Modelling control of meiotic recombination frequency
--------------------------------------------------
Meiotic recombination generates novel combinations of genetic variation via reciprocal exchange between homologous chromosomes. To better understand this process we are generating genome-wide recombination frequency maps in the model plant Arabidopsis thaliana.
The research associate will integrate recombination frequency maps with genomic, epigenomic and population genetic data. They will then develop a quantitative model for control of recombination frequency, which will be tested using experimental genetics. This research has important implications for population genetics and food security via crop breeding.
The research associate will work jointly within Dr Ian Henderson's experimental research group and the Departmental Bioinformatics Group led by Dr Krys Kelly. The bioinformatics group currently consists of five people developing statistical methodology and analysing genome-wide patterns of small RNAs and epigenetic information in association with Prof Sir David Baulcombe.
Applicants should have a Ph.D and substantial experience of a statistical language (e.g. R, Matlab). Experience in statistics, statistical genetics, quantitative genetics or genomics would also be beneficial.
Vacancy Reference No: PD09942. Salary: £27,319-£35,646 pa.
The post is available for 2 years, in the first instance.
Download the further particulars and details of how to apply from http://www.plantsci.cam.ac.uk/jobs/index.html.
Closing date is 12 noon on 16 December 2011.