Hi,
I've just received the sequencing results from 6 exome-seq experiments.
The samples come from human patients.
Would you recommend aligning the samples on hg19 or hg38?
Have you all switched to hg38, or do you still use hg19?
Is hg19 still better annotated, and does it still have more related datasets facilitating downstream analyses?
I will launch the alignment based on your recommendations.
Sorry if the answer is obvious.
I haven't done any exome-seq analyses since the release of hg38.
Thank
I've just received the sequencing results from 6 exome-seq experiments.
The samples come from human patients.
Would you recommend aligning the samples on hg19 or hg38?
Have you all switched to hg38, or do you still use hg19?
Is hg19 still better annotated, and does it still have more related datasets facilitating downstream analyses?
I will launch the alignment based on your recommendations.
Sorry if the answer is obvious.
I haven't done any exome-seq analyses since the release of hg38.
Thank
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