Hi,
I have analyzed my Illumina data using Mosaik and generated a list of SNPs using Gigabayes. I would like to look for nonsynonymous SNPs so I filtered the data to limit the analysis to SNPs within Exons (approximately 1500 SNPs). I am now trying to identify which SNPs cause amino acid substitutions (nsSNPs). Are there any analysis tools or pipelines to automate the process of SNP to amino acid substitutions calling? Any help would be greatly appreciated.
Thanks
-John
I have analyzed my Illumina data using Mosaik and generated a list of SNPs using Gigabayes. I would like to look for nonsynonymous SNPs so I filtered the data to limit the analysis to SNPs within Exons (approximately 1500 SNPs). I am now trying to identify which SNPs cause amino acid substitutions (nsSNPs). Are there any analysis tools or pipelines to automate the process of SNP to amino acid substitutions calling? Any help would be greatly appreciated.
Thanks
-John
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