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Old 01-13-2014, 06:37 AM   #1
giuliano stirparo
Junior Member
 
Location: Italy

Join Date: Nov 2011
Posts: 6
Default Time series issue,no time 0!

Hi everybody
I have encountered a problem during analysis of time series data.
I particular, in my data, I have 2 condition(in replicates) and 4 time.
Quote:
drug 1h Placebo 1h
drug 1h Placebo 1h
drug 2h Placebo 2h
drug 2h Placebo 2h
drug 3h Placebo 3h
drug 3h Placebo 3h
drug 4h Placebo 4h
drug 4h Placebo 4h
As you can see I have no time 0 in my analysis and I was wondering if I should use pairwise comparisons or GLMs?
That is because if I use GLMs, I assume no difference at time 1h, but I know that there are!
On the other side if I use pairwise comparisons I lose the modulation through the time!
I hope that my explanation is clear!
Any ideas?

Thank you

Giuliano
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