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Old 06-07-2011, 01:04 PM   #1
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Default TopHat closure based search and coverage based search

I am very new to NGS analysis and TopHat. Could someone please explain to me what closure based search and coverage based search exactly mean? I read the manuscript and the manual, but still couldn't figure it out.
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Old 03-27-2012, 01:47 AM   #2
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I wonder this as well. It's really difficult to find information about these two parameters in tophat.
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