TopHat closure based search and coverage based search

tasteandsee · 06-07-2011, 01:04 PM

Hi,
I am very new to NGS analysis and TopHat. Could someone please explain to me what closure based search and coverage based search exactly mean? I read the manuscript and the manual, but still couldn't figure it out.
Thanks,
TS

glados · 03-27-2012, 01:47 AM

I wonder this as well. It's really difficult to find information about these two parameters in tophat.

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06-07-2011, 01:04 PM	#1
tasteandsee Junior Member Location: US Join Date: Jun 2011 Posts: 1	TopHat closure based search and coverage based search Hi, I am very new to NGS analysis and TopHat. Could someone please explain to me what closure based search and coverage based search exactly mean? I read the manuscript and the manual, but still couldn't figure it out. Thanks, TS

03-27-2012, 01:47 AM	#2
glados Member Location: Aperture Science Join Date: Mar 2012 Posts: 59	I wonder this as well. It's really difficult to find information about these two parameters in tophat.