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i downloaded reads per million data from gdc portal for aml patient and i need to know whether the data is pair ended or single ended. how do i find out?
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Search for experimental and analysis protocols used to generate the data.
So first try to find the detailed description of their experimental and data analysis protocols and pipelines used to generate the results you've downloaded.
Also try downloading some aml RNAseq bam files from the GDL portal and digging into their headers...
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The sequencing world is rapidly changing due to declining costs, enhanced accuracies, and the advent of newer, cutting-edge instruments. Equally important to these developments are improvements in sequencing analysis, a process that converts vast amounts of raw data into a comprehensible and meaningful form. This complex task requires expertise and the right analysis tools. In this article, we highlight the progress and innovation in sequencing analysis by reviewing several of the...Yesterday, 07:48 AM -
The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...04-22-2024, 07:01 AM
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