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We are looking for a Genomics Research Scientist with experience in Illumina protocols. This hire would be responsible for sample quality control, library preparation and run setup on the HiSeq 2500 and MiSeq.
Here is the job listing from NYUMC:
The Genome Technology Core (GTC) is a fee-for-service laboratory operated by the NYU Langone Medical Center as a state-of-the-art shared resource for biomedical researchers. The GTC staff members provide their knowledge and expertise in a broad variety of service-type genomics applications to the research community at NYULMC. They work closely with investigators to define optimal experimental design, develop and maintain standards for all service procedures and troubleshooting, and provide guidance and service in data management and analysis.
Under the direct supervision of the Director of GTC, the Assistant Research Scientist will be responsible for performing a variety of complex laboratory tasks and standardized procedures to provide high quality genomics resource support for the research community
PRINCICIPAL DUTIES & RESPONSIBILITIES
1. Responsible for assisting with installation, implementation and operation of highly specialized equipment and instrumentation in the GTC shared resource laboratory, including lab automation
2. Responsible for the sample handling, preparation, QC analysis and analytical processing to generate high quality data for further analysis and interpretation.
3. Accountable for own and delegated activities, including responsibility for parts of GTC operation in the absence of the Director
4. Participates actively in experimental design
5. Responsible for optimizing, implementing and daily performance of standard operating procedures for the next-generation sequencing (NGS), as follows:
a. Illumina MiSeq and HiSeq for next-generation sequencing-- primary instrument operation and maintenance responsibilities.
b. Develop full workflows for DNA, RNA and custom targets library preparation and library QC for Illumina MiSeq and HiSeq2000 sequencing.
c. Perform QPCR analysis for library preps for all NGS workflows
d. Develop and optimize high throughput library preparation using lab automation.
e. Operation of Illumina cBot -- cluster generation station for the above instruments
6. Analysis (quality and quantity) of nucleic acids for downstream applications of next-generation sequencing, including Agilent Bioanalyzer and picogreen quantitation.
7. Participates actively in developing, and implementing approved new procedures, or modifications to existing policies and procedures, including ordering, and record keeping for billing purposes.
REQUIRMENTS
Minimum hiring qualifications is a M.S. with at least two years of experience. Experience with NGS sequencing, library preparation and lab automation is strongly preferred. In addition to the responsibilities and duties of Assistant Research Scientist listed above, the candidate is expected to perform all general and advanced procedures within the lab with minimal or no supervision. He/she will assist in the planning of experiments as well as in the interpretation of the results. The Assistant Research Scientist is expected to train and provide supervision to junior level lab personnel in established laboratory policies, methods, and procedures. He/she is also expected to use specific software in the analysis and interpretation of the results of experiments. It is expected that an Assistant Research Scientist in the Genome Technology Center has and will be continuously building both the knowledge and experience in specific areas such as Biochemistry, Molecular Biology, lab automation and genomics-oriented bioinformatics etc.
Here is the job listing from NYUMC:
The Genome Technology Core (GTC) is a fee-for-service laboratory operated by the NYU Langone Medical Center as a state-of-the-art shared resource for biomedical researchers. The GTC staff members provide their knowledge and expertise in a broad variety of service-type genomics applications to the research community at NYULMC. They work closely with investigators to define optimal experimental design, develop and maintain standards for all service procedures and troubleshooting, and provide guidance and service in data management and analysis.
Under the direct supervision of the Director of GTC, the Assistant Research Scientist will be responsible for performing a variety of complex laboratory tasks and standardized procedures to provide high quality genomics resource support for the research community
PRINCICIPAL DUTIES & RESPONSIBILITIES
1. Responsible for assisting with installation, implementation and operation of highly specialized equipment and instrumentation in the GTC shared resource laboratory, including lab automation
2. Responsible for the sample handling, preparation, QC analysis and analytical processing to generate high quality data for further analysis and interpretation.
3. Accountable for own and delegated activities, including responsibility for parts of GTC operation in the absence of the Director
4. Participates actively in experimental design
5. Responsible for optimizing, implementing and daily performance of standard operating procedures for the next-generation sequencing (NGS), as follows:
a. Illumina MiSeq and HiSeq for next-generation sequencing-- primary instrument operation and maintenance responsibilities.
b. Develop full workflows for DNA, RNA and custom targets library preparation and library QC for Illumina MiSeq and HiSeq2000 sequencing.
c. Perform QPCR analysis for library preps for all NGS workflows
d. Develop and optimize high throughput library preparation using lab automation.
e. Operation of Illumina cBot -- cluster generation station for the above instruments
6. Analysis (quality and quantity) of nucleic acids for downstream applications of next-generation sequencing, including Agilent Bioanalyzer and picogreen quantitation.
7. Participates actively in developing, and implementing approved new procedures, or modifications to existing policies and procedures, including ordering, and record keeping for billing purposes.
REQUIRMENTS
Minimum hiring qualifications is a M.S. with at least two years of experience. Experience with NGS sequencing, library preparation and lab automation is strongly preferred. In addition to the responsibilities and duties of Assistant Research Scientist listed above, the candidate is expected to perform all general and advanced procedures within the lab with minimal or no supervision. He/she will assist in the planning of experiments as well as in the interpretation of the results. The Assistant Research Scientist is expected to train and provide supervision to junior level lab personnel in established laboratory policies, methods, and procedures. He/she is also expected to use specific software in the analysis and interpretation of the results of experiments. It is expected that an Assistant Research Scientist in the Genome Technology Center has and will be continuously building both the knowledge and experience in specific areas such as Biochemistry, Molecular Biology, lab automation and genomics-oriented bioinformatics etc.
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