My project:
A 10000bp region on chromsome 1 of human, soelxa sequencing this region of 50 individuals,
How can I estimate Pi (nucleartide diversity) ?
I know there are at list 3 factors effect :
1. sequencing error
2. alignment error
3. number of sequences be sequenced per individual is random
A 10000bp region on chromsome 1 of human, soelxa sequencing this region of 50 individuals,
How can I estimate Pi (nucleartide diversity) ?
I know there are at list 3 factors effect :
1. sequencing error
2. alignment error
3. number of sequences be sequenced per individual is random
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