Hi,
I have a list of SNP resulting from exome Re-Sequencing of tumor/normal human samples and GATK analyses. Now I searching Softwaretools for prediction (or better ) which analyse Mutation effect on Protein domain.
found:
1. SNP@DOMAIN (be no more available)
2. sift
3. ConDel
4. CanPredit
5. MutPred
6. polyphen and (2)
7. phastCons and GERP
All of this tools are not satisfactory for protein domain results. It is possible to combine one of the tools with databases like KEGG to get domains? Or is there another tool to handle this? Have someone further ideas to overcome this?
airtime
I have a list of SNP resulting from exome Re-Sequencing of tumor/normal human samples and GATK analyses. Now I searching Softwaretools for prediction (or better ) which analyse Mutation effect on Protein domain.
found:
1. SNP@DOMAIN (be no more available)
2. sift
3. ConDel
4. CanPredit
5. MutPred
6. polyphen and (2)
7. phastCons and GERP
All of this tools are not satisfactory for protein domain results. It is possible to combine one of the tools with databases like KEGG to get domains? Or is there another tool to handle this? Have someone further ideas to overcome this?
airtime
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