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Old 02-02-2011, 06:05 AM   #1
sylvesterholt
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Location: Copenhagen

Join Date: Feb 2011
Posts: 1
Default Aligning against two yeast genomes?

Dear all

I am making a research proposal, and looking into RNA-Seq for metatranscriptomics of 2 different yeasts in the same sample (S. cerevisiae + L. thermotolerans). I know, it should be possible to map against two genomes, but I would like to hear your ideas. What is the best way/tools to use? It will be ether on Illumina Genome analyzer IIx or 454 Genome Sequencer FLX.

Thanks
Sylvester
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