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  • Avadis NGS version 1.2 available now!

    Version 1.2 incorporates new features, some bug fixes, and several enhancements, most importantly the following:
    • Differential SNP analysis has been added to the RNA-Seq and DNA-Seq workflows to identify the SNP locations in a pair of samples (such as in matched tumor-normal) that exhibit differential behavior.
    • Insertions discovered during SNP detection are now annotated with a decibel score.
    • Aligned sequence data generated by the PacBio and Ion Torrent platforms can now be imported into Avadis NGS, in addition to the Illumina, SOLiD, and 454 platforms.
    • Import option for continuous data in the wiggle .WIG file format, allowing users to import and visualize data including GC percentage and conservation scores. These tracks have been added to the human annotation data (h18 and hg19 builds) and will be added to the annotations for organisms currently supported by Avadis NGS. Annotations can be updated through the Annotations Manager.
    • The novel gene detection algorithm has been enhanced to make better use of spliced and paired reads. Novel partition predictions are now annotated with conservation scores derived from the conservation continuous data track.
    • The novel gene detection algorithm has been enhanced to make better use of spliced and paired reads. Novel partition predictions are now annotated with conservation scores derived from the conservation continuous data track.
    • Improvements to the determination of length of translocations and zygosity of structural variants (SV) as part of the SV Detection analysis step in the DNA-Seq workflow.
    • Region lists can now be imported from TSV files and region lists of any size are now supported by all operations.
    • The first six scripts in our online Scripts Library can now be accessed directly from the application.


    The full list of enhancements, bug fixes and know issues is available here or through the Help Menu in Avadis NGS.

    All current users of version 1.1.1 will be automatically prompted for a product update the next time Avadis NGS is launched.

    To evaluate this new version request a trial on our website, then go to the Download Installers section and select the appropriate installer for your operating system. For guidance on software installation and activation there are a number of online guides available on our website or you can contact our support team.

    The Avadis NGS Team
    Last edited by Strand SI; 04-17-2011, 10:31 PM.

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