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Position title:
“Next Generation” Personalised Healthcare: novel cancer biomarker and target selection from long non-coding RNA
Location:
Oncology iMED, Alderley Park, Cheshire, UK.
Candidate Focus & Challenge:
Candidate Knowledge, Skills & Experience:
We are seeking a highly motivated post-doc with Next Generation Sequencing bioinformatics expertise to generate and characterise novel lncRNA cancer biomarker hypotheses across priority cancer drug candidates
This posting will close on 11th October 2013
This position is initially a 2 year fixed term contract.
Due to the high volume of Post Doctoral positions being advertised globally within AZ, we require you to state on your covering letter any other positions within the business globally which you have recently applied for quoting the appropriate reference number.
How to apply
Apply online at the AstraZeneca careers website
“Next Generation” Personalised Healthcare: novel cancer biomarker and target selection from long non-coding RNA
Location:
Oncology iMED, Alderley Park, Cheshire, UK.
Candidate Focus & Challenge:
- Generate novel and testable lncRNA biomarker hypotheses across selected drug candidates in the AZ oncology portfolio through development and application of novel bioinformatics approaches to Next Generation Sequencing datasets
- Functionally characterise candidate biomarkers using cutting-edge bioinformatics techniques.
- Challenge and influence current personalised healthcare strategies across the AZ oncology portfolio
- Interface with scientists from across many disciplines while at the same time being able to work independently.
- Communicate results both within AstraZeneca via global working groups and externally at meetings and through publications in high impact journals
- Work collaboratively with other experts internally within Bioinformatics and Disease Biology groups, and externally with academic partners
Candidate Knowledge, Skills & Experience:
We are seeking a highly motivated post-doc with Next Generation Sequencing bioinformatics expertise to generate and characterise novel lncRNA cancer biomarker hypotheses across priority cancer drug candidates
- Essential
- PhD level in a computational biology, bioinformatics or equivalent biology subject
- Experience of applying bioinformatics approaches to cancer datasets.
- Familiarity with Unix/Linux operating systems.
- Highly competent in one or more of Perl, Python, Ruby, Java, C/C++, R programming languages.
- Expertise in the application, analysis and interpretation of Next Generation Sequencing data particularly RNA-Seq.
- Strong interpersonal, organizational and communication skills.
- Proven ability to independently design and execute incisive experiments and interpret results.
- Good track record of driving and publishing scientific research.
- Desirable
- Experience of in silico lncRNA identification and interpretation
- Disease area and/or domain knowledge in Biological Sciences or similar
- Interdisciplinary background in bioinformatics/computational biology and cancer genomics .
- Experience in applying systems biology approaches to large data sets.
- Additional
- Strong passion and commitment to drug discovery and delivering therapies for patients.
- Evidence of innovative approach to working and driving ideas through publication.
- A strong scientific track record, as evidenced by published or accepted papers in well recognized peer-reviewed journals, oral and/or poster presentations at scientific meetings.
- Ability to work well within a group/team environment.
This posting will close on 11th October 2013
This position is initially a 2 year fixed term contract.
Due to the high volume of Post Doctoral positions being advertised globally within AZ, we require you to state on your covering letter any other positions within the business globally which you have recently applied for quoting the appropriate reference number.
How to apply
Apply online at the AstraZeneca careers website