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  • Whole Exome analysis on a 1500 € standard PC, is that possible?

    Whole-Exome Analysis on a Mainstream Desktop PC
    We are regularly asked what kind of computer is needed to analyze Whole Exome data. We have tested it for you!



    Analysing NGS data usually is the domain of power compute servers or High-Performance Clusters, as it typically has massive volume and requires a lot of data crunching. However, the power of available CPUs is increasing, and now there are faster processors with more cores available on the market at competitive prices. This applies not only to the sector of the server “workhorses” but also to the sector of “standard” Desktop PCs. This sector is characterized by commodity hardware that is produced in high volumes and can be bought at affordable prices. While this kind of PC used to have just a single core, it is today possible to buy Desktop CPUs with as many as 16 cores.

    Given the price premium that is necessary to enter the high-performance server sector, the question arises: why not use commodity hardware for NGS data analysis? So we started an experiment: how feasible is it to do a resource-intensive whole-exome sequencing (WES) analysis on a modern Desktop PC.

    read more
    ecSeq Bioinformatics is Europe’s leading provider of hands-on bioinformatics workshops and professional data analysis in the field of Next-Generation Sequencing (NGS).

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  • seqadmin
    Recent Advances in Sequencing Analysis Tools
    by seqadmin


    The sequencing world is rapidly changing due to declining costs, enhanced accuracies, and the advent of newer, cutting-edge instruments. Equally important to these developments are improvements in sequencing analysis, a process that converts vast amounts of raw data into a comprehensible and meaningful form. This complex task requires expertise and the right analysis tools. In this article, we highlight the progress and innovation in sequencing analysis by reviewing several of the...
    05-06-2024, 07:48 AM
  • seqadmin
    Essential Discoveries and Tools in Epitranscriptomics
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    The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...
    04-22-2024, 07:01 AM

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