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Old 12-02-2012, 07:41 AM   #1
Fad2012
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Location: UK

Join Date: Sep 2012
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Default How to install NCBI BLAST 2.2.27+ on mac OS X 10.8.1

Dear all,

I am trying to install the latest BLAST+ 2.2.27+ following the instruction on the following page which is provided from NCBI :

http://www.ncbi.nlm.nih.gov/books/NBK52640/

However, i am now completely lost, as they mention on the page that:

To do BLAST searches on platforms lacking precompiled blast+ package will require compiling the BLAST source code. The source code file, "ncbi-blast-#.#.#+-src" in either zip or gziped tar format, is available from the same ftp directory as blast+ packages. Questions and feedbacks on source code compilation should be addressed to: toolbox@ncbi.nlm.nih.gov.

This is the first time for me to deal with local BLAST, and i know that my system is lacking the precompiled blast+. I want to know how to compile the BLAST+ and then configure the BLAST. When i try to configure it as it is mentioned on the page above, all the time i receive error messages such as: No such file or directory, or command not found.

ANY SUGGESTIONS OR HELP PLEASE!

Thanks very much.
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Old 12-02-2012, 03:35 PM   #2
maubp
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Location: Dundee, Scotland, UK

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Unless you have a strong reason to do so, don't bother compiling BLAST+ yourself - just use the pre-compiled binaries from the NCBI. They work fine and it is far easier - just decompress the tar-ball, and move/copy the binaries to somewhere on your path:
ftp://ftp.ncbi.nlm.nih.gov/blast/exe...blast+/LATEST/
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