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  • Why do human genome studies use bwa 0.5.9?

    Many papers in human genetics including published in this year have used bwa 0.5.9 for HiSeq reads mapping instead of upper versions.

    Why do they use the old one?

  • #2
    Because the work was probably done some years ago and it's only just been published. There's quite a lag between sequencing and publication - possibly the lifetime of a 3 year grant.

    And the performance on 100 base reads probably isn't that different to later versions anyway.

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