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Old 01-06-2020, 05:02 PM   #1
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Location: HKG

Join Date: Jan 2020
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Default GWAS (genome wide association study)


Im new to SNP studies and Im looking to clear a few doubts.

There are several studies identifying SNPs near gene loci via genome wide association studies (GWAS). I understand a SNP is significant if it has a genome wide significance of P < 5 10−8

If a particular SNP has been identified e.g.

rs2487032 (A), p value 9.20 10−14 in disease vs control samples in GWAS

Does this mean that anyone in the population with this SNP

rs2487032 (A) has a high association with that particular disease, if the allele in place is A?
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