SEQanswers

Go Back   SEQanswers > Literature Watch



Similar Threads
Thread Thread Starter Forum Replies Last Post
PubMed: Strategies for Exome and Genome Sequence Data Analysis in Disease Gene Discov Newsbot! Literature Watch 0 05-28-2011 11:13 AM
PubMed: The use of ultra-dense array CGH analysis for the discovery of micro-copy num Newsbot! Literature Watch 0 01-29-2011 10:50 AM
PubMed: Quantification of Gene Transcripts with Deep Sequencing Analysis of Gene Expr Newsbot! Literature Watch 0 01-13-2011 02:00 AM
PubMed: Gene discovery using massively parallel pyrosequencing to develop ESTs for th Newsbot! Literature Watch 0 05-21-2009 05:02 AM

Reply
 
Thread Tools
Old 11-09-2011, 10:20 AM   #1
Newsbot!
RSS Posting Maniac
 

Join Date: Feb 2008
Posts: 1,443
Default PubMed: In silico analysis of the exome for gene discovery.

Syndicated from PubMed RSS Feeds

In silico analysis of the exome for gene discovery.

Methods Mol Biol. 2011;760:109-28

Authors: Hinchcliffe M, Webster P

Abstract
Here we describe a bioinformatic strategy for extracting and analyzing the list of variants revealed from an exome sequencing project to identify potential disease genes. This in silico method filters out the majority of common SNPs and extracts a list of potential candidate protein-coding and non-coding RNA (ncRNA) genes. The workflow employs Galaxy, a publically available Web-based software, to filter and sort sequence variants identified by capture-based target enrichment and sequencing from exomes including selected ncRNAs.


PMID: 21779993 [PubMed - indexed for MEDLINE]



More...
Newsbot! is offline   Reply With Quote
Reply

Thread Tools

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off




All times are GMT -8. The time now is 03:12 AM.


Powered by vBulletin® Version 3.8.9
Copyright ©2000 - 2020, vBulletin Solutions, Inc.
Single Sign On provided by vBSSO