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Old 08-01-2013, 11:17 AM   #1
Location: Downtown Toronto

Join Date: Nov 2010
Posts: 37
Default Bioinformatician - Ontario Institute for Cancer Research

Position: Bioinformatician
Site: MaRS Centre, South Tower
101 College Street, Suite 800
Toronto, Ontario, Canada M5G 0A3
Department: Informatics and Bio-computing
Reports To: Principal Investigator, Informatics & Bio-computing (Dr. P. Boutros)
Salary: $58,000 per annum
Hours: 35 Hrs/week
Status: Full-time, Permanent

The Ontario Institute for Cancer Research (OICR) is seeking a Bioinformatician to work with the Informatics and Bio-computing team.

Are you an expert in next-generation sequencing? The Ontario Institute for Cancer Research (OICR) is seeking a talented Bioinformatician to focus on the analysis of large next-gen sequencing datasets. The successful candidate will have an extensive interest in large-data problems, and an in-depth knowledge of data-handling. This position also involves a very substantial analysis component. The successful candidate will be working closely with systems administrators, statisticians, PhD students, and post-doctoral associates on:

• Optimization and parallelization of algorithms for the analysis of genome-sequencing data;
• Integration of diverse datasets into unified statistical models;
• Automating procedures for pipeline evaluation and assessment;
• Automation of routine programming and data-analysis tasks; and
• Downstream data-modeling, including pathway analysis and clinical association studies.

The successful candidate will be working on the Canadian Prostate Cancer Genome Network (CPC-GENE), a project studying 500 prostate cancer patients. Via this project, the research team is generating multiple independent genomic analyses, including mRNA and DNA microarrays, RNA-seq, whole genome-sequencing (PacBio and Illumina Hi-Seq), and some limited RNAi functional screen data. Rich clinical annotation is available on these samples. Analyses are performed on cutting-edge IT infrastructure including a multi-petabyte storage system and a >6,500-core compute farm.


• University degree in computational biology, engineering, mathematics, computer sciences or molecular biology
• Strong background with Unix/Linux tools and administration required
• Exposure to next-generation sequencing data required
• Experience in high performance computing on a large scale cluster using Sun Grid Engine (SGE)
• Experience in software and database programming (e.g., R, Perl, SQL)
• Experience working with test-driven programming and version control preferred
• Proven experience with bioinformatics resources and/or databases preferred
• Statistical background in machine-learning, survival or Bayesian techniques is an asset
• Knowledge of molecular and/or cancer biology is an asset

OICR is an innovative cancer research institute located in the MaRS Centre in the Discovery District in downtown Toronto. OICR is addressing significant challenges in cancer research with multi-disciplinary, multi-institutional teams. New discoveries to prevent, detect and treat cancer will be moved from the bench to practical applications in patients. The OICR team is growing quickly. We are innovative, dedicated professionals who bring expertise to each of our roles. We are looking for individuals interested in being part of a culture of excellence that will result in Ontario being recognized internationally as a leading jurisdiction for cancer research.

Launched in December 2005, OICR is an independent institute funded by the Government of Ontario through the Ministry of Research and Innovation.

For more information about OICR, please visit the website at

POSTED DATE: August 13, 2013
CLOSING DATE: Posted Until Filled

Interested candidates may apply here

OICR has a diverse workforce and is an equal opportunity employer.

The Ontario Institute for Cancer Research thanks all applicants. However, only those under consideration will be contacted.
Resume Format: If you elect to apply, you will need a text or HTML version of your resume so that you can cut and paste it into the application box provided. Before you submit the completed application, you will be asked to attach one or two files to your application. Please attach your resume as a .doc file.

OICR Benefit Plan as of March 1, 2013

Vacation: Three (3) paid weeks per year
Sick: Ten (10) paid days per year

SunLife Group Benefits
Effective Date of Coverage:
The waiting period for your group benefits plan is three (3) months continuous employment.
Life Schedule: Two (2) times Annual Basic earnings
Maximum $500,000

Dependent Life: $5,000/spouse

Long Term Disability: Graded Schedule
Maximum $7,500

Extended Health: Deductible – NIL
Semi-private Hospital – 100%
Prescription Drugs 80% (drug card provided)
Paramedical at 80% Maximum $500 per practitioner
Chiropractic at 80% Maximum $500 per practitioner
Hospital Out-of-Country 100% – EMERGENCY ONLY

Dental: Deductible – NIL
80% Maximum $2,000 for each individual covered
Pre-determination if over $500

Vision Care: 100% Maximum of $300 in any 12-month period for a person under age 18 or in any 24-month period for any other person for eyeglasses, contact lenses or laser eye correction surgery

Pension Plan (HOOPP)
Effective Date of Coverage:

Member contributes 6.9% on earnings up to $50,100 and 9.2% on earnings greater than $50,100.

Last edited by eandrade; 08-14-2013 at 06:34 AM.
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