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Hi all,
I was wondering if anyone has used MuTect to call variants from RNA-seq data? I have total RNA-seq data for tumor and matched normal samples, and am wondering if MuTect would work. As expression of some genes maybe really high, I was thinking of removing those from the analysis.
or perhaps, just using the haplotype caller would be a better option!
Anyone have any thoughts.
Thanks
I was wondering if anyone has used MuTect to call variants from RNA-seq data? I have total RNA-seq data for tumor and matched normal samples, and am wondering if MuTect would work. As expression of some genes maybe really high, I was thinking of removing those from the analysis.
or perhaps, just using the haplotype caller would be a better option!
Anyone have any thoughts.
Thanks