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Old 08-28-2018, 08:47 AM   #1
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Location: WashU

Join Date: Aug 2010
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Default WASHU Postdoctoral Research Associate

WASHU Postdoctoral Research Associate - Pediatrics Hematology/Oncology

This position is in the Department of Pediatrics Hematology/Oncology. This position is for the Medical School Campus.


The laboratory of Dr. Joshua B. Rubin is looking for a highly motivated and well-trained individual to work as a postdoctoral fellow on a newly-funded funded project examining the functions of p53 variants of unknown significance. The work will prioritize variants that occur in human cancer and focus on characterizing their transcriptional activity, and their regulation of proliferation, DNA repair, and apoptosis. An analysis for cell sex-specific effects of each variant will be performed as a component of the Rubin labís ongoing focus on sex differences in cancer biology. Development of cell-based, high-throughput, assays for p53 functions will be required. Familiarity with cell culture and cell-based assays, or development of high-throughput screening tools, or sequence analysis, will be considered an advantage. This is a grant-supported position in the Department of Pediatrics at the Washington University School of Medicine, a leading research institution.

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