Desktop PC specs, and Server specs for MiSeq, PGM, and Proton

eosin · 04-18-2012, 09:14 PM

Hi!

We're starting up a sequencing lab with MiSeq, PGM, and Proton on it. I'm really new here, so I need help regarding this matter.

Question:

We plan to buy 4 PC's for our staff, what specs can you recommend for those PC's?

Server. What specs are the best for a server that's going to handle viral, bacterial, and eukaryotic (for proton) genomes?

Our first project is going to be on whole genome sequencing of viral DNA.

colindaven · 04-19-2012, 03:58 AM

The server - running linux - should have plenty of attached storage. Perhaps 30-40TB to start with.
IBM DS3500 systems are cheap and effective storage workhorses. We have found our 24 core servers to be critical when running multi threaded aligner applications.

Network: We have found 1Gbit dedicated network to be sufficient (Solid 5500xl data), though storage and server interconnects should be 6Gbit+.

Cooling: is tricky. We have had good experiences with the APC InRow water cooled system.

For desktops it depends if you are running lots of applications on them, or do a lot on the server. We have everything from dual cores to 8 core Xeons. Storage again is important, and 2TB is nice.

GenoMax · 04-19-2012, 05:43 AM

Considering the memory prices these days get as much RAM as you can afford for the PC's for staff. It would help if they are planning to do any analysis on them.

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04-18-2012, 09:14 PM	#1
eosin Junior Member Location: Philippines Join Date: Mar 2012 Posts: 7	Desktop PC specs, and Server specs for MiSeq, PGM, and Proton Hi! We're starting up a sequencing lab with MiSeq, PGM, and Proton on it. I'm really new here, so I need help regarding this matter. Question: We plan to buy 4 PC's for our staff, what specs can you recommend for those PC's? Server. What specs are the best for a server that's going to handle viral, bacterial, and eukaryotic (for proton) genomes? Our first project is going to be on whole genome sequencing of viral DNA.

04-19-2012, 03:58 AM	#2
colindaven Senior Member Location: Germany Join Date: Oct 2008 Posts: 415	The server - running linux - should have plenty of attached storage. Perhaps 30-40TB to start with. IBM DS3500 systems are cheap and effective storage workhorses. We have found our 24 core servers to be critical when running multi threaded aligner applications. Network: We have found 1Gbit dedicated network to be sufficient (Solid 5500xl data), though storage and server interconnects should be 6Gbit+. Cooling: is tricky. We have had good experiences with the APC InRow water cooled system. For desktops it depends if you are running lots of applications on them, or do a lot on the server. We have everything from dual cores to 8 core Xeons. Storage again is important, and 2TB is nice.

04-19-2012, 05:43 AM	#3
GenoMax Senior Member Location: East Coast USA Join Date: Feb 2008 Posts: 7,080	Considering the memory prices these days get as much RAM as you can afford for the PC's for staff. It would help if they are planning to do any analysis on them.