SEQanswers

Go Back   SEQanswers > Bioinformatics > Bioinformatics

Similar Threads
Thread Thread Starter Forum Replies Last Post
Cufflinks/Cuffdiff different FPKM values for multiple genes at one location id0 Bioinformatics 7 11-11-2013 03:29 AM
cuffdiff (v 2.1.1) p-values nsl Bioinformatics 4 06-03-2013 10:25 PM
cummeRbund andplotting for selected treatments among multiple treatments ataheri RNA Sequencing 1 04-10-2013 07:41 PM
cuffdiff q values jk1124 RNA Sequencing 4 01-04-2013 09:38 AM
Cuffdiff producing q-values > 1 ocs Bioinformatics 7 08-15-2012 11:26 AM

Reply
 
Thread Tools
Old 03-04-2014, 03:01 PM   #1
gwilymh
Member
 
Location: Milwaukee

Join Date: Dec 2011
Posts: 72
Default Are Cuffdiff q-values and p-values reliable when multiple treatments are analyzed?

Does anyone know if the q- and p-values output by CuffDiff are reliable when more than two treatments are compared in the the analysis.

Generating q-values for each gene in a two-treatment study is fairly strait forward. However, in a five-treatment study where each pair of treatments is compared, there are 15 pairwise comparisons for each gene. Can these comparisons be lumped together to generate the q-values, or should each pair of treatments be analyzed independently?
gwilymh is offline   Reply With Quote
Old 03-16-2014, 12:32 PM   #2
tpitz
Junior Member
 
Location: italy

Join Date: Mar 2014
Posts: 1
Default

Can anyone anwer this? Thank you
tpitz is offline   Reply With Quote
Reply

Tags
cuffdiff, cufflinks, p-value, q-value, treatment

Thread Tools

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off




All times are GMT -8. The time now is 01:08 PM.


Powered by vBulletin® Version 3.8.9
Copyright ©2000 - 2021, vBulletin Solutions, Inc.
Single Sign On provided by vBSSO