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Old 04-11-2011, 04:41 AM   #1
Location: Downtown Toronto

Join Date: Nov 2010
Posts: 37
Default Postdoctoral Fellow, Computational Cancer Biology

Position: Postdoctoral Fellow, Computational Cancer Biology
Site: MaRS Centre, Toronto
Department: Informatics & Biocomputing
Reports To: Dr. Paul Boutros
Salary: Commensurate with level of experience
Hours: 35 Hrs/week
Status: Full-Time Contract, 2 years

The Ontario Institute for Cancer Research (OICR) is seeking a postdoctoral fellow in Computational Cancer Biology in the laboratory of Dr. Paul Boutros at the Ontario Institute for Cancer Research (OICR). This position involves the analysis of data from a very large ICGC project to study the genomes and transcriptomes of 500 prostate cancer patients. We have generated multiple independent genomic analyses of a cohort of colon cancer patients, including mRNA and DNA microarrays, RNA-seq (ABI SOLiD), whole genome-sequencing (PacBio and Illumina Hi-Seq), and some limited RNAi functional screen data. Rich clinical annotation is also available on these samples, and the successful candidate will work in a collaborative team of biologists, computer scientists, and statisticians on the integrative analysis of all these datasets. Projects can include aspects of methods development, pre-processing and univariate statistical analyses, and integrative systems biology. Analysis of these data will be performed on cutting-edge IT infrastructure including a multi-petabyte storage system and a 6,500-core compute farm.

A PhD in computational biology, engineering, mathematics, computer sciences or molecular biology;
Statistical background, such as machine-learning, survival or Bayesian techniques;
Strong experience in software and database programming (R, Perl, SQL);
Knowledge of biological sequence algorithmic and analysis tools;
Strong knowledge of molecular biology. Knowledge of cancer biology is an asset;
Team-player, interested in working in a fast-paced and highly collaborative environment with biologists, computer scientists, statisticians, and clinicians;
Previous postdoctoral training in any of these fields is an asset, but not required.

OICR is an innovative cancer research institute located in the MaRS Centre in the Discovery District in downtown Toronto. OICR is addressing significant challenges in cancer research with multi-disciplinary, multi-institutional teams. New discoveries to prevent, detect and treat cancer will be moved from the bench to practical applications in patients. The OICR team is growing quickly. We are innovative, dedicated professionals who bring expertise to each of our roles. We are looking for individuals interested in being part of a culture of excellence that will result in Ontario being recognized internationally as a leading jurisdiction for cancer research.

Launched in December 2005, OICR is an independent institute funded by the Government of Ontario through the Ministry of Research and Innovation.

For more information about OICR, please visit the website at

POSTED DATE: April 7, 2011
CLOSING DATE: May 7, 2011

Interested candidates may apply here

OICR has a diverse workforce and is an equal opportunity employer.

The Ontario Institute for Cancer Research thanks all applicants. However, only those under consideration will be contacted. Candidates will be expected to provide their current employer as a reference.

Resume Format: If you elect to apply, you will need a text or HTML version of your resume so that you can cut and paste it into the application box provided. Before you submit the completed application, you will be asked to attach one or two files to your application. Please attach your resume as a .doc or .pdf file.
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