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  • In Sequence: Yale Team Uses an Illumina GA to Sequence Yeast Transcriptome; Finds Gre

    Syndicated from In Sequence RSS Feed

    Sequencing fragmented cDNAs on Illumina’s Genome Analyzer and mapping the reads to the yeast genome, the scientists identified untranslated regions, introns, alternative initiation codons, upstream open reading frames, unexpected 3’ ends, and overlapping genes. The results, which appeared online in Science last week, indicate that “the yeast transcriptome is more complex than previously appreciated,” the researchers write in their study, and pave the way for similar analyses of the human genome.

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  • seqadmin
    Strategies for Sequencing Challenging Samples
    by seqadmin


    Despite advancements in sequencing platforms and related sample preparation technologies, certain sample types continue to present significant challenges that can compromise sequencing results. Pedro Echave, Senior Manager of the Global Business Segment at Revvity, explained that the success of a sequencing experiment ultimately depends on the amount and integrity of the nucleic acid template (RNA or DNA) obtained from a sample. “The better the quality of the nucleic acid isolated...
    03-22-2024, 06:39 AM
  • seqadmin
    Techniques and Challenges in Conservation Genomics
    by seqadmin



    The field of conservation genomics centers on applying genomics technologies in support of conservation efforts and the preservation of biodiversity. This article features interviews with two researchers who showcase their innovative work and highlight the current state and future of conservation genomics.

    Avian Conservation
    Matthew DeSaix, a recent doctoral graduate from Kristen Ruegg’s lab at The University of Colorado, shared that most of his research...
    03-08-2024, 10:41 AM

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