SEQanswers

Go Back   SEQanswers > Literature Watch



Similar Threads
Thread Thread Starter Forum Replies Last Post
Plotting length distribution of contigs? kga1978 Bioinformatics 2 01-16-2012 01:22 AM
PubMed: Single-molecule direct RNA sequencing without cDNA synthesis. Newsbot! Literature Watch 0 10-01-2011 02:00 AM
PubMed: An Integrated System for DNA Sequencing by Synthesis Using Novel Nucleotide A Newsbot! Literature Watch 0 02-04-2010 02:11 AM
PubMed: Statistical distributions of sequencing by synthesis with probabilistic nucle Newsbot! Literature Watch 0 06-16-2009 05:00 AM
PubMed: Genome-wide massively parallel sequencing of formaldehyde fixed-paraffin embe Newsbot! Literature Watch 0 05-15-2009 05:00 AM

Reply
 
Thread Tools
Old 06-13-2012, 02:00 AM   #1
Newsbot!
RSS Posting Maniac
 

Join Date: Feb 2008
Posts: 1,443
Default PubMed: Length distribution of sequencing by synthesis: fixed flow cycle model.

Syndicated from PubMed RSS Feeds

Length distribution of sequencing by synthesis: fixed flow cycle model.

J Math Biol. 2012 Jun 12;

Authors: Kong Y

Abstract
Sequencing by synthesis is the underlying technology for many next- generation DNA sequencing platforms. We developed a new model, the fixed flow cycle model, to derive the distributions of sequence length for a given number of flow cycles under the general conditions where the nucleotide incorporation is probabilistic and may be incomplete, as in some single-molecule sequencing technologies. Unlike the previous model, the new model yields the probability distribution for the sequence length. Explicit closed form formulas are derived for the mean and variance of the distribution.


PMID: 22689207 [PubMed - as supplied by publisher]



More...
Newsbot! is offline   Reply With Quote
Reply

Thread Tools

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off




All times are GMT -8. The time now is 02:16 AM.


Powered by vBulletin® Version 3.8.9
Copyright ©2000 - 2020, vBulletin Solutions, Inc.
Single Sign On provided by vBSSO