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We are planing to move to Solexa from 454, the problem is if it is possible to get a good assemble from only Solexa data for the human Mitochondrial DNA(17Kb, circular, no repetitive element)?
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I have seen good assembly for plant mitochondrial DNA using 35bp reads. The fact that there's no repetitive element makes it easier. -
Do you have the reference paper?Comment
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Oops...my mistake. What I saw is chloroplast DNA (~160kb) not mitochondrial DNA. I think it's not published yet.Comment
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I asked some experts, it seems highly possible, although nobody publish it yet.
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We have sequenced human mito DNA on the Illumina and get very good results.Comment
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Hi Bruce,
What's your software to do the assembling?Comment
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