HI
I have performed reference based consensus generation. Next I have mapped back reads to consensus and performed SNP calling. Surprisingly I am getting ~15% homozygous SNPs. Is it possible to get homozygous SNPs when we are mapping reads back to consensus ?
I have performed reference based consensus generation. Next I have mapped back reads to consensus and performed SNP calling. Surprisingly I am getting ~15% homozygous SNPs. Is it possible to get homozygous SNPs when we are mapping reads back to consensus ?
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