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  • HugeSeq Pipeline

    Does anyone have experience using the HugeSeq pipeline (link below)?


    The tools in the pipeline are pretty mainstream (eg BWA, SAMtools, GATK, BreakDancer, Pindel, CNVnator, and BreakSeq), but I haven't found anybody discussing it on the forum. It's nice that somebody integrated these programs as part of a free software package.

    Any thoughts on this software?

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  • seqadmin
    Essential Discoveries and Tools in Epitranscriptomics
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    The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist on Modified Bases...
    Yesterday, 07:01 AM
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    Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...
    04-04-2024, 04:25 PM

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