Seqanswers Leaderboard Ad

Collapse

Announcement

Collapse
No announcement yet.
X
 
  • Filter
  • Time
  • Show
Clear All
new posts

  • Best place to get .vcf with genotypes for HapMap cell lines?

    Hi

    I need to obtain SNPs and genotypes for 30 lymphoblastoid cell lines.

    I had been told these 30 individuals (CEU and YRI) had all been genotyped as part of the 1000genomes project, however this turns out not to be true: in the last 1000genomes iteration I can only find .vcf files for 16 of my individuals. Some of the missing 14 appear to have been part of the project at some point, however there is no trace of them in the current dataset.

    I have then looked in Omni 2.5 data, again part of the 1000genomes data. Here I find vcf for a total of 23 individuals, a superset of the 16 individuals I mentioned before.

    So I'm still short of data for 7 individuals. I think hapmap should have data for these, but I'm not sure. Do I have any other alternatives? If hapmap is my only option, what is the best way to get .vcf files with genotypes from the hapmap project for these 7 individuals (and possibly for all 30 of them, for coherence reasons)?

    Thank you in advance for your help!

Latest Articles

Collapse

  • seqadmin
    Essential Discoveries and Tools in Epitranscriptomics
    by seqadmin


    The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist on Modified Bases...
    Yesterday, 07:01 AM
  • seqadmin
    Current Approaches to Protein Sequencing
    by seqadmin


    Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...
    04-04-2024, 04:25 PM

ad_right_rmr

Collapse

News

Collapse

Topics Statistics Last Post
Started by seqadmin, 04-11-2024, 12:08 PM
0 responses
39 views
0 likes
Last Post seqadmin  
Started by seqadmin, 04-10-2024, 10:19 PM
0 responses
41 views
0 likes
Last Post seqadmin  
Started by seqadmin, 04-10-2024, 09:21 AM
0 responses
35 views
0 likes
Last Post seqadmin  
Started by seqadmin, 04-04-2024, 09:00 AM
0 responses
55 views
0 likes
Last Post seqadmin  
Working...
X