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  • Thank you SEQanswers

    Before I flood the forums with questions, I would like to make a first post to say Hello and Thank You.

    I have been doing bioinformatics for over 10 years now but just recently got handed a project using Illumina 76bp sequencing to study the metabolome of human gut bacteria and am finding myself in too deep. Since I am the only bioinformatician where I work, I am very relieved to find this site.

    It is always good to see that I am not alone (in my confusion and frustration) and it awesome to see that so many great people have come here to share experiences and expertise.

    So I am off to continue reading as many threads as I can before I post my first noob questions .

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    The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...
    04-22-2024, 07:01 AM
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    Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...
    04-04-2024, 04:25 PM

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